Berthold Detection Systems, your partner for luminescence measurement - Berthold Detection Systems, your partner for luminescence measurement -
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Smart Line - Smart Card Single Tube Luminometer
 
The Smart Line Tube Luminometer changes the way to run your luminescent assay:
- Insert Assay Card
- Insert sample
- Obtain result
 
Assay Card Concept
The Assay Card based protocol management concept makes the Smart Line TL an easy to use
instrument. A smart card with an embedded memory chip stores all assay protocol parameters
and protects them from any unauthorized manipulation.
The benefits:
The Assay Card is the key to a specific measurement and evaluation procedure. Several assays can be established without any modification at the instrument. Straight forward user dialog guides the user through even complex measurement sequences.
 
Applications
The Smart Line TL is a stand-alone workstation for flash and glow luminescence applications performed in single tube format including:
Qualitative Luminescent Immunoassays
Competitive Luminescent Immunoassays (LIA) (bound + free fraction)
Immuno-Luminometric Assays (ILMA)
DNA/RNA Probe Assays
 
Performance
The Smart Line TL luminometer is designed for low to medium throughput level. It is a small, user-
friendly instrument that combines a distinctive mechanical design with advanced photon counting
electronics and a highly sensitive detector. The unique sample chamber design makes certain that the samples are always loaded properly and effortlessly. The sample holder optimizes light collection. It guarantees the correct positioning of each sample and ensures homogeneous sensitivity.
For the best possible sensitivity, the detector is located under the sample chamber in very close proximity to the sample. The photon counting electronics provide the lowest signal background and the highest linearity.
 
Injection System
Smart Line TL can be equipped with up to two high precision reagent injectors. Variable injection speed and precise injector positioning allow the homogenous mixing of reagents for every type of sample, including coated tubes, coated beads and magnetic particles. The injector lines are built of chemically inert materials. The Smart Line TL is equipped with reliable, bellow type injector pumps. The unique Smart Line TL design permits easy service access to all components of the injection system. Priming and cleaning of the injection lines in Smart Line TL is an easy and error proof procedure. All necessary priming and cleaning sequences can be stored on individual smart cards.
 
Data Evaluation
Built-in-Software

The Luminometer is capable of processing both qualitative and quantitative assays. The on board software supports automatic data processing by utilizing settings stored on Assay Card.
Qualitative data reduction. Employs Cut-Off calculation algorithm with complete set of negative, positive and undecided criteria to classify samples.
Quantitative data reduction. Full standard curve using up to 10 standards. Optional re-use of standard curve with 2-point calibration. Involves several curve fitting algorithms:
- Regression
- Smoothed cubic spline
- Four - Parameter Logistics (4 PL)
 
PC Software
For creating, saving and reading protocols on chip card: Generation of Cut-off protocol, Quantitative data reduction protocol, Kinetics protocol, LightCheck protocol, Priming protocol. 
 
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